When scientists discovered breastmilk plus a probiotic might ward off the inflammation responsible for necrotising enterocolitis – a devastating disease that affects 10% of preterm infants – they quickly launched a follow-on study to learn more.
These scientists have now found that the combination not only has anti-inflammatory effects, but also anti-viral effects and the potential to regulate healthy growth and development of immature intestinal cells. This further reinforces the possibility that breastmilk plus a probiotic could prevent and potentially treat NEC.
Their findings have just been published by Scientific Reports in this open access article, ‘The impact of indole-3-lactic acid on immature intestinal innate immunity and development: a transcriptomic analysis’.
The Family Larsson-Rosenquist Foundation is a grateful, partial sponsor of this work by the Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Harvard Medical School, the Institute of Agro-Product Processing, Jiangsu Academy of Agricultural Sciences and the Department of Pediatrics, Kangnam Sacred Heart Hospital, Hallym University College of Medicine.
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